Specialization and Targeting of B-Type Cyclins
نویسندگان
چکیده
منابع مشابه
the investigation of the relationship between type a and type b personalities and quality of translation
چکیده ندارد.
Specialization of B - Type Cyclins for Mitosis or Meiosis in S . c e r e a e
The CLBl , CLB2, and CLB3 genes encode Btype cyclins important for mitosis n Saccharomyces cerevisiae, while a fourth Btype cyclin gene, CLB4, has no clear role. The effects of homozygous clb mutations on meiosis were examined. Mutants homozygous for clbl clb3, or for clbl clb4, gave high levels of sporulation, but produced mainly two-spored asci instead of four-spored asci. The cells had compl...
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D-type cyclins (cyclins D1, D2, and D3) promote G1-S progression and are aberrantly expressed in cancer. We reported previously that all-trans-retinoic acid chemo-prevented carcinogenic transformation of human bronchial epithelial (HBE) cells through proteasomal degradation of cyclin D1. Retinoic acid is shown here to activate distinct mechanisms to regulate different D-type cyclins in HBE cell...
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Declarative models and language concepts for the coordination in parallel and distributed systems attract increasing attention because of their simplicity and expressiveness. In this paper, type specialization is proposed as a declarative, object-oriented programming and coordination model. A simple execution mechanism repeatedly specializes types of entities (variables) and thereby collects kn...
متن کاملSic1 plays a role in timing and oscillatory behaviour of B-type cyclins.
Budding yeast cell cycle oscillates between states of low and high cyclin-dependent kinase activity, driven by association of Cdk1 with B-type (Clb) cyclins. Various Cdk1-Clb complexes are activated and inactivated in a fixed, temporally regulated sequence, inducing the behaviour known as "waves of cyclins". The transition from low to high Clb activity is triggered by degradation of Sic1, the i...
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ژورنال
عنوان ژورنال: Molecular Cell
سال: 1999
ISSN: 1097-2765
DOI: 10.1016/s1097-2765(00)80183-5